Melinda Haley Halliwell - Bethany Joy Galeotti
Clark Kent - Tom Welling
Nathan scott -  James Lafferty
Brooke davis -  Sophia Bush
Lana Lang/Luthor -  Kristin Kreuk
Lucas Scott - Chad Michael Murray
Lex Luthor -  Michael Rosenbaum
Chloe Sullivan - Allison Mack
Lionel Luthor -  John Glover
Jimmy Olsen -  Aaron Ashmore

 
GUEST STAR
 
Piper,Phoebe e Paige Halliwell - Holly Marie Combs, Alyssa Milano e Rose McGowan
Peyton Sawyer - Hillary Burton
Wyatt Matthew Halliwell - Wes Ramsey
Chris Halliwell - Drew Fuller
Leo Wyatt - Brian Krause
Billie Jenkins - Kaley Cuoco
Jake - Bryan Greenberg